Acetylcholine
esterase (AchE) is the enzyme that catalyzes the breakdown of Acetylcholine.
Acetylchiline esterase inhibitors are the drugs that stops the destruction of
Ach, thus the overdose of it or poisoning mainly causes the parasympathetic
actions.
Simple mnemonic for this is DUMBBEELSS.
DUMBBEELSS stands for Diarrhea, Urination, Miosis, Bradycardia,
Bronchochonstriction, Emesis, Excitation, Lacrimation, Salivation &
Sweating.
The antidote for AchE Inhibitor poisoning is Atropine.
Pralidoxime is used for regeneration
of AchE.
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